Speaking of the difficulties when the company was just established, Dr. Yang Feng clearly remembered a series of questions before him at that time, such as "where does the capital come from", "how to recruit employees", "how to realize the operation"... from a medical idea to the process of industrialization, it can be said that there are many difficulties. In addition to solving the various problems that follow, Dr. Yang Feng's primary task is to concentrate on his main business,Only focusing on scientific research, upgrading product lines and developing mature industrialized technologies is the company's core competitiveness..

The drug delivery nanoliposome technology was still in the blank stage in the domestic market at that time, and through the research and development of the core team headed by Dr. Yang Feng,A modified methotrexate and its preparation method and application have entered the substantive examination stage. EventuallyThe company's core technology has been tempered and upgraded, successfully breaking the core technical barriers, the first batch of products produced by Wuhan company can be successfully delivered to customers.

In August 2019, Dr. Yang Feng decided to expand the company to the periphery of Wuhan in order to further enhance the company's R & D and production capabilities. Yichang has a certain biomedical industry foundation and has become his first choice.

At that time, Dr. Yang Feng inspected a number of industrial plants in Yichang. After many connections between Yichang Investment Promotion Bureau and Peng Pai, general manager of the park, Dr. Yang Feng fully understood Yichang's preferential policies in terms of talent recruitment, taxation and other aspects, as well as the park's ability as a private incubator to give maximum support after the enterprise settled down. These olive branches finally moved Dr. Yang Feng and decided to settle in Yichang bio-pharmaceutical incubator in mid-August for great development.

Dr. Yang Feng met with Peng Pai, general manager of the park for the first time. Peng Pai said that if you have any ideas, please tell me directly and we will try our best to solve them. The enterprise has two demands. First, it will carry a bag to settle in on October 1, and the decoration expenses need to be paid in advance by the park. Second, due to the current tight capital turnover, landing hopes to give rent concessions. Seeing the high growth of the enterprise and the leading level of the industry, the park first advances the 1.1 million to renovate and decorate the office buildings, and at the same time offers rent concessions to the enterprise in the form of share discounts. For Dr. Yang Feng, time is money, and even one day late for production is a huge loss to the company.

In a short period of one and a half months, 2000 square meters of office buildings were renovated, which fulfilled the demand of enterprises to settle in with high efficiency and also met the requirements of enterprises to produce when they came in.After entering, the park management personnel quickly assisted Dr. Yang Feng to apply for a provincial-level special expert in Hubei Province. After the application was successful, they assisted in applying for a "talent room" to solve Dr. Yang Feng's housing worries."Peng Zong did what he said, honest and pragmatic, so that we can rest assured, feel at ease and be satisfied." Yang Feng said.

After learning that Boren Kairun Pharmaceutical currently has some research and development results and good market prospects, but has not yet been able to enjoy the support of policies and projects, the park management personnel quickly contacted the cooperative intermediary patent firm to help the company optimize intellectual property., And actively prepare to declare high; The park management personnel also accompanied the enterprise to the high-tech zone section.The creation bureau, the municipal science and technology bureau and other departments asked the department heads to review and coach the materials, and the high-level declaration is expected to be completed in 2021. In addition, the park also assists enterprises in reportingYichang High-tech Zone High-end Talent Leading Characteristic Carrier Project, for special funds of 1.8 million yuan. After understanding the difficulty of recruitment, help enterprises to connect with the School of Biology and Pharmacy of China Three Gorges University to recruit undergraduate and master students in bioengineering to meet the needs of professional and technical personnel.

Dr. Yang Feng graduated from the Chinese Academy of Sciences with a doctorate, majoring in the synthesis and application of carbohydrates. Not long after the establishment of the company, I received a phone call from the vice president of the company on a business trip, saying with indignation that I would fire an employee. It turned out that an employee of the company called a meeting with a vice president of the company and criticized the vice president in public. Although I think it's incredible, it really happened. Dr. Yang Feng thinks it's not too big, so he can't digest it internally. As a result, after the beginning of the year, the employee took annual leave and paid leave, and took a month's salary to pat his ass and leave.

If you look at it carefully, there must be something wrong with the management of the company because of the employees' challenge and irresponsibility when leaving. Due to the lack of attention and tolerance at the beginning, in the absence of clear institutional constraints, various situations occurred frequently. Later, the company issued various incentive policies and internal management documents, through continuous trial and error, improvement, to find a management system suitable for its own company development. At present, the company's internal management gradually tends to be standardized and process-oriented.

In addition to the need to improve management, enterprises have an increasing demand for technology and talents.

 It has to be said that in many cases, the quality, ability and style of enterprise managers, and the ability of self-reflection, transformation and transformation determine the "ceiling" of the enterprise ".

After the large-scale development of the company, it is not only the management system that needs to be broken through, but the self that needs to be changed. From academic research to the management of the enterprise, from the change of the way of thinking... Every step is a self-breakthrough.

Along the way, Dr. Yang Feng has contacted many investors. However, most of them are not very optimistic about the enterprises. First, the small scale is not worth investing in. Second, the feedback enterprises are not broad enough. Dr. Yang Feng said here with a smile, investors will take other corporate financing to compare, the prospects of the enterprise a blue ocean, can see the future doubling of the profit situation ...... and so on, and Dr. Yang Feng's business is the hands of the business first focus, the proposed financing needs are more focused on the present. Reality gives a fatal blow, in the eyes of investors these are not optimistic. But in the author's understanding, this is more reflected in the down-to-earth pragmatic enterprises.

Although affected by the financing environment, Dr. Yang Feng was not discouraged. It was his business strategy to achieve further growth through steady operation. Next, he will focus on the company's incentive policies for educating and retaining people, which will help to accelerate the company's growth by accelerating capital accumulation.Committed to becoming a new benchmark for the development of China's drug delivery industry.

It is not easy to start a business, but it is even more difficult to keep it. Before starting a business, Dr. Yang Feng analyzed the market and understood the industry; at the beginning of starting a business, he thought about countermeasures and solved difficult problems; after starting a business, he explored, summarized, and clarified the future development direction.

After several years of rapid development and systematic management, Boren Kairun has now formed an integrated biomedical enterprise integrating R & D, production and sales. The company's products have been sold to Novartis, Lilly, Kanglong into dozens of well-known enterprises at home and abroad. In the words of Dr. Yang Feng, the product does not worry about sales, but the production capacity cannot keep up. At present, the company's annual order loss rate is about 1/3. The company's technical employees are new, and orders are crowded together. Although very helpless, but the cultivation of professional talents needs time precipitation, the company's self-built plant to achieve industrialization development needs the accumulation of original funds.

"Although there is an order loss every year, the technical level of the product is excellent, and the stickiness of the enterprise has been very high." Dr. Yang Feng introduced. at present,The company has a wide user base in industries such as new targeted drugs, pharmaceuticals and diagnostic reagents, and has developed thousands of polyethylene glycol linker products.The company's market share is developing at a high speed with a growth rate of more than 30%. The company is also developing new nano-liposome chemotherapy drug anti-tumor preparation technology, and is preparing to expand the production capacity of the bio-industrial park in the past five years to realize the development of industrialization.Looking to the future and achieving a meaningful career is Yang Feng's future goal.

On the road of both opportunities and crises in entrepreneurship, Dr. Yang has come to this day not only because of his profound professional knowledge, his diligence, agility and pragmatism, but also because of finding the right path suitable for the development of his own enterprise. Every key step is steady.

Whether it is business management, or business management, financing... Many things in Yang Feng's view, are not overnight success. Can endure the loneliness of entrepreneurship,Only by day-to-day refinement and taking the entrepreneurial process as a kind of self-experience and transformation can we go further in the future.